An efficient method to construct the A,B-rings component toward total syntheses of phycocyanobilin and its derivative as a photoprobe

被引：18

作者：

Jayasundera, KP ^{[1
]}

Kinoshita, H ^{[1
]}

Inomata, K ^{[1
]}

机构：

[1] Kanazawa Univ, Grad Sch Nat Sci & Technol, Dept Chem Sci, Kanazawa, Ishikawa 9201192, Japan

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 2000年 / 73卷 / 02期

关键词：

D O I：

10.1246/bcsj.73.497

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Total syntheses of phycocyanobilin and its derivative bearing a photoreactive group at the D-ring were accomplished by developing a new and efficient method for the construction of A,B-rings component, which consists of the Wittig-type new coupling reaction of 4-(1-methoxyethyl or 1-tosylethyl)-3-methyl-5-tosyl-1,5-dihydro-2H-pyrrol-2-one and a 2-formyl pyrrole derivative in the presence of (Bu3P)-Bu-n and a base, followed by reduction with aluminum amalgam and a subsequent acid or base treatment.

引用

页码：497 / 505

页数：9

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