Enantioselective allylation of aldehydes promoted by chiral zinc bis(oxazoline) complexes

被引：48

作者：

Cozzi, PG

Orioli, P

Tagliavini, E

UmaniRonchi, A

机构：

[1] Dipartimento Chimico G.Ciamician, Università di Bologna, 40126 Bologna

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 01期

关键词：

D O I：

10.1016/S0040-4039(96)02238-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In this paper we introduce a simple, new system for promoting enantioselective catalytic allylation of aldehydes. Chiral bis(oxazalinyl) zinc complexes have been shown to catalyze the allylation of aldehydes in good yield when allyl tributyltin is used as the nucleophile. The values of e.e. obtained for this reaction are in the range of 40-46%. A number of different reaction conditions were screened and the results obtained with other metal systems are also reported. Copyright (C) 1996 Elsevier Science Ltd

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页码：145 / 148

页数：4

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