Compact, high voltage power supply for the lab-on-a-chip

被引:13
作者
Collins, GE
Wu, P
Lu, Q
Ramsey, JD
Bromund, RH
机构
[1] USN, Res Lab, Div Chem, Washington, DC 20375 USA
[2] So Oregon Univ, Dept Phys, Ashland, OR 97520 USA
[3] Geocenters Inc, Lanham, MD 20706 USA
[4] Coll Wooster, Dept Chem, Wooster, OH 44691 USA
来源
LAB ON A CHIP | 2004年 / 4卷 / 04期
关键词
D O I
10.1039/b314349j
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The design, construction and operation of a simple, inexpensive and compact high voltage power supply (HVPS) for use in conjunction with a simple cross capillary electrophoresis microchip is presented. The microchip HVPS utilizes a single high voltage power supply (15 kV), a voltage-divider network, to give the voltages necessary to operate a gated injection valve, and two high voltage relays for switching between the open and closed gate sequences of the injection. In order to accommodate the application of different simple cross microchip dimensions, a set of equations for defining the resistor network and ensuring proper gate performance are presented.
引用
收藏
页码:408 / 411
页数:4
相关论文
共 6 条
[1]   Rapid prototyping of microfluidic systems in poly(dimethylsiloxane) [J].
Duffy, DC ;
McDonald, JC ;
Schueller, OJA ;
Whitesides, GM .
ANALYTICAL CHEMISTRY, 1998, 70 (23) :4974-4984
[2]   Computer simulations of electrokinetic injection techniques in microfluidic devices [J].
Ermakov, SV ;
Jacobson, SC ;
Ramsey, JM .
ANALYTICAL CHEMISTRY, 2000, 72 (15) :3512-3517
[3]   Versatile 3-channel high-voltage power supply for microchip capillary electrophoresis [J].
García, CD ;
Liu, Y ;
Anderson, P ;
Henry, CS .
LAB ON A CHIP, 2003, 3 (04) :324-328
[4]   Portable high-voltage power supply and electrochemical detection circuits for microchip capillary electrophoresis [J].
Jackson, DJ ;
Naber, JF ;
Roussel, TJ ;
Crain, MM ;
Walsh, KM ;
Keynton, RS ;
Baldwin, RP .
ANALYTICAL CHEMISTRY, 2003, 75 (14) :3643-3649
[5]   Minimizing the number of voltage sources and fluid reservoirs for electrokinetic valving in microfluidic devices [J].
Jacobson, SC ;
Ermakov, SV ;
Ramsey, JM .
ANALYTICAL CHEMISTRY, 1999, 71 (15) :3273-3276
[6]   MICROCHIP CAPILLARY ELECTROPHORESIS WITH AN INTEGRATED POSTCOLUMN REACTOR [J].
JACOBSON, SC ;
KOUTNY, LB ;
HERGENRODER, R ;
MOORE, AW ;
RAMSEY, JM .
ANALYTICAL CHEMISTRY, 1994, 66 (20) :3472-3476