Genetic evidence supports secondary metabolic diversity in Prochloron spp., the cyanobacterial symbiont of a tropical ascidian

被引：50

作者：

Schmidt, EW ^{[1
]}

Sudek, S

Haygood, MG

机构：

[1] Univ Utah, Dept Med Chem, Salt Lake City, UT 84112 USA

[2] Univ Calif San Diego, Scripps Inst Oceanog, La Jolla, CA 92093 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 08期

关键词：

D O I：

10.1021/np049948n

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Didemnid family ascidians commonly harbor obligate cyanobacterial symbionts, Prochloron spp., which have been proposed to biosynthesize cyclic peptides. Here, it is shown that Prochloron spp. do indeed contain genes for nonribosomal peptide biosynthesis, although genes for cyclic peptide biosynthesis have not yet been characterized. A peptide synthetase-containing open reading frame of unknown function was cloned from the Prochloron symbionts of some didemnid ascidians, but not from others. These data indicate that Prochloron spp. have variable secondary metabolic potential.

引用

页码：1341 / 1345

页数：5

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