Current concepts of the pathophysiology of migraine

被引：73

作者：

Goadsby, PJ

机构：

[1] Institute of Neurology, London WC1N 3BG, Queen Square

来源：

NEUROLOGIC CLINICS | 1997年 / 15卷 / 01期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0733-8619(05)70293-0

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Migraine is a common and debilitating disorder. The relatively recent characterization of the anatomy and physiology of the pain-sensitive innervation of the cranium provides a framework with which to understand the manifestations of migraine and treatment. This article reviews the pathophysiology of migraine from a clinical standpoint, emphasizing features that are seen or may be integrated into clinical practice. Some discussion of treatment options is included in a setting of clarifying relationships between drug action and migraine pathophysiology.

引用

收藏

页码：27 / +

页数：1

相关论文

共 99 条

[11] CONTINGENT NEGATIVE-VARIATION IN HEADACHE [J].

DENOORDHOUT, AM ;

TIMSITBERTHIER, M ;

SCHOENEN, J ;

TIMSIT, M .

ANNALS OF NEUROLOGY, 1986, 19 (01) :78-80

[12]

DIMITRIADOU V, 1991, NEUROSCIENCE, V44, P97

[13]

DOWSON A, 1995, CEPHALALGIA S14, V15, P173

[14] EXTRA-CRANIAL VASCULAR CHANGES AND THE SOURCE OF PAIN IN MIGRAINE HEADACHE [J].

DRUMMOND, PD ;

LANCE, JW .

ANNALS OF NEUROLOGY, 1983, 13 (01) :32-37

[15]

DUCROS A, 1995, CEPHALALGIA S14, V15, P9

[16] CEREBRAL BLOOD-FLOW IN MIGRAINE [J].

EDMEADS, J .

HEADACHE, 1977, 17 (04) :148-152

[17] MODIFICATION OF VASOCONSTRICTOR RESPONSES IN CEREBRAL BLOOD-VESSELS BY LESIONING OF THE TRIGEMINAL NERVE - POSSIBLE INVOLVEMENT OF CGRP [J].

EDVINSSON, L ;

OLESEN, IJ ;

KINGMAN, TA ;

MCCULLOCH, J ;

UDDMAN, R .

CEPHALALGIA, 1995, 15 (05) :373-383

[18] PEPTIDERGIC INNERVATION OF THE CEREBRAL-CIRCULATION - ROLE IN SUBARACHNOID HEMORRHAGE IN MAN [J].

EDVINSSON, L ;

UDDMAN, R ;

JUUL, R .

NEUROSURGICAL REVIEW, 1990, 13 (04) :265-272

[19]

Edvinsson L, 1986, NEURAL REGULATION BR, P407

[20] INCREASE IN PLASMA CALCITONIN-GENE-RELATED PEPTIDE FROM THE EXTRACEREBRAL CIRCULATION DURING NITROGLYCERIN-INDUCED CLUSTER HEADACHE ATTACK [J].

FANCIULLACCI, M ;

ALESSANDRI, M ;

FIGINI, M ;

GEPPETTI, P ;

MICHELACCI, S .

PAIN, 1995, 60 (02) :119-123

← 1 2 3 4 5 6 7 8 9 10 →