Identification of a mouse orthologue of the G-protein-coupled receptor SALPR and its expression in adult mouse brain and during development

被引：19

作者：

Boels, K ^{[1
]}

Hermans-Borgmeyer, I ^{[1
]}

Schaller, HC ^{[1
]}

机构：

[1] Univ Hamburg, Zentrum Mol Neurobiol, D-20246 Hamburg, Germany

来源：

DEVELOPMENTAL BRAIN RESEARCH | 2004年 / 152卷 / 02期

关键词：

SALPR; GPCR135; GPR100; orphan GPCRs; CNS expression;

D O I：

10.1016/j.devbrainres.2004.06.002

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The mouse orthologue of somatostatin and angiotensin-like peptide receptor (SALPR) was amplified from cDNA of the hippocampal cell line HT22. It coded for a protein of 472 amino acids showing 84% sequence identity with human SALPR and 43% with human G-protein-coupled receptor 100 (GPR100). A distinct pattern of expression in brain, spinal cord, and dorsal root ganglia during development and in the mature brain hint at important functions of SALPR for differentiation and maintenance of the nervous system. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：265 / 268

页数：4

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