Polyphenol Conjugates and Human Health: A Perspective Review

被引:132
作者
Cirillo, Giuseppe [1 ]
Curcio, Manuela [1 ]
Vittorio, Orazio [2 ,3 ]
Iemma, Francesca [1 ]
Restuccia, Donatella [1 ]
Spizzirri, Umile Gianfranco [1 ]
Puoci, Francesco [1 ]
Picci, Nevio [1 ]
机构
[1] Univ Calabria, Dept Pharm Hlth & Nutr Sci, I-87036 Arcavacata Di Rende, CS, Italy
[2] Univ New S Wales, Childrens Canc Inst Australia, Lowy Canc Res Ctr, Sydney, NSW 2052, Australia
[3] Univ New S Wales, Australian Ctr NanoMed, Sydney, NSW 2052, Australia
关键词
Polyphenols; bio-conjugates; biological properties; polymers; nanomaterials; GREEN TEA POLYPHENOL; LACCASE-CATALYZED SYNTHESIS; ANTIOXIDANT ACTIVITY; ENZYMATIC-SYNTHESIS; GALLIC ACID; (-)-EPIGALLOCATECHIN GALLATE; HELICOBACTER-PYLORI; CEREBRAL-ISCHEMIA; CURCUMIN ANALOGS; MEDICINAL-PLANTS;
D O I
10.1080/10408398.2012.752342
中图分类号
TS2 [食品工业];
学科分类号
100403 [营养与食品卫生学];
摘要
In recent years, antioxidants have gained great importance because of their potential use in food, pharmaceutical, and cosmetic industries. This interest is rooted in the cumulative evidence connecting active oxygen and free radicals with numerous human degenerative disorders, such as cardiovascular diseases, cancer, aging, and atherosclerosis. Polyphenols are the major class of antioxidant able to reduce the oxidative damages of lipids, proteins, enzymes, carbohydrates, and DNA in living cells and tissues. Among the realm of polyphenol compounds, polyphenol conjugates have been proposed as innovative materials which, by combining the advantageous properties of both the components, can increase the efficiency of antioxidants and their range of application in nutritional and biomedical fields. This work is an overview of the different class of polyphenol conjugates, which will be analyzed in terms of nutritional and biological properties, showing how these bio-conjugates will positively affect the human health.
引用
收藏
页码:326 / 337
页数:12
相关论文
共 111 条
[1]
STRONG ATTENUATION OF ISCHEMIC AND POSTISCHEMIC BRAIN EDEMA IN RATS BY A NOVEL FREE-RADICAL SCAVENGER [J].
ABE, K ;
YUKI, S ;
KOGURE, K .
STROKE, 1988, 19 (04) :480-485
[2]
Epigallocatechin, a green tea polyphenol, attenuates myocardial ischemia reperfusion injury in rats [J].
Aneja, R ;
Hake, PW ;
Burroughs, TJ ;
Denenberg, AG ;
Wong, HR ;
Zingarelli, B .
MOLECULAR MEDICINE, 2004, 10 (1-6) :55-62
[3]
Inhibitory Potential of Tea Polyphenolics and Influence of Extraction Time Against Helicobacter pylori and Lack of Inhibition of Beneficial Lactic Acid Bacteria [J].
Ankolekar, Chandrakant ;
Johnson, David ;
Pinto, Marcia da Silva ;
Johnson, Kevin ;
Labbe, Ronald ;
Shetty, Kalidas .
JOURNAL OF MEDICINAL FOOD, 2011, 14 (11) :1321-1329
[4]
Free radical biology - terminology and critical thinking [J].
Azzi, A ;
Davies, KJA ;
Kelly, F .
FEBS LETTERS, 2004, 558 (1-3) :3-6
[5]
FREE-RADICALS AND THE ETIOLOGY OF COLON CANCER [J].
BABBS, CF .
FREE RADICAL BIOLOGY AND MEDICINE, 1990, 8 (02) :191-200
[6]
EGCG attenuates AMPA-induced intracellular calcium increase in hippocampal neurons [J].
Bae, JH ;
Mun, KC ;
Park, WK ;
Lee, SR ;
Suh, SI ;
Baek, WK ;
Yim, MB ;
Kwon, TK ;
Song, DK .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2002, 290 (05) :1506-1512
[7]
Resveratrol prevents endothelial nitric oxide synthase uncoupling and attenuates development of hypertension in spontaneously hypertensive rats [J].
Bhatt, Siddhartha R. ;
Lokhandwala, Mustafa F. ;
Banday, Anees Ahmad .
EUROPEAN JOURNAL OF PHARMACOLOGY, 2011, 667 (1-3) :258-264
[8]
Bravo L, 1998, NUTR REV, V56, P317, DOI 10.1111/j.1753-4887.1998.tb01670.x
[9]
Enzymatic Synthesis and Characterization of PolyQuercetin [J].
Bruno, Ferdinando F. ;
Trotta, Adam ;
Fossey, Stephen ;
Nagarajan, Subhalakshmi ;
Nagarajan, Ramaswamy ;
Samuelson, Lynne A. ;
Kumar, Jayant .
JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY, 2010, 47 (12) :1191-1196
[10]
Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer [J].
Cai, YZ ;
Luo, Q ;
Sun, M ;
Corke, H .
LIFE SCIENCES, 2004, 74 (17) :2157-2184