Quantitative structure-activity relationships in substrates, inducers, and inhibitors of cytochrome P4501 (CYP1)

被引：47

作者：

Lewis, DFV

机构：

[1] Molecular Toxicology Research Group, School of Biological Sciences, University of Surrey, Guildford

来源：

DRUG METABOLISM REVIEWS | 1997年 / 29卷 / 03期

关键词：

D O I：

10.3109/03602539709037593

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

[No abstract available]

引用

页码：589 / 650

页数：62

共 64 条

[51] BINDING OF 3-METHYLCHOLANTHRENE AND 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN TO A COMMON AH-RECEPTOR SITE IN MOUSE AND RAT HEPATIC CYTOSOLS [J].

OKEY, AB ;

VELLA, LM .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1982, 127 (01) :39-47

[52] METABOLIC-ACTIVATION OF CARCINOGENS AND TOXIC-CHEMICALS [J].

PARKE, DV ;

IOANNIDES, C ;

LEWIS, DFV .

HUMAN TOXICOLOGY, 1988, 7 (05) :397-404

[53]

PARKE DV, 1986, TOXICOLOGY EUROPE YE, P14

[54] 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN AND RELATED HALOGENATED AROMATIC-HYDROCARBONS - EXAMINATION OF THE MECHANISM OF TOXICITY [J].

POLAND, A ;

KNUTSON, JC .

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1982, 22 :517-554

[55]

POLAND A, 1976, J BIOL CHEM, V251, P4936

[56] IDENTIFICATION OF THE AH RECEPTOR NUCLEAR TRANSLOCATOR PROTEIN (ARNT) AS A COMPONENT OF THE DNA-BINDING FORM OF THE AH RECEPTOR [J].

REYES, H ;

REISZPORSZASZ, S ;

HANKINSON, O .

SCIENCE, 1992, 256 (5060) :1193-1195

[57] COMPARATIVE CARCINOGENICITY OF THE PAHS AS A BASIS FOR ACCEPTABLE EXPOSURE LEVELS (AELS) IN DRINKING-WATER [J].

RUGEN, PJ ;

STERN, CD ;

LAMM, SH .

REGULATORY TOXICOLOGY AND PHARMACOLOGY, 1989, 9 (03) :273-283

[58] EFFECTS OF STRUCTURE ON BINDING TO THE 2,3,7,8-TCDD RECEPTOR PROTEIN AND AHH INDUCTION - HALOGENATED BIPHENYLS [J].

SAFE, S ;

BANDIERA, S ;

SAWYER, T ;

ZMUDZKA, B ;

MASON, G ;

ROMKES, M ;

DENOMME, MA ;

SPARLING, J ;

OKEY, AB ;

FUJITA, T .

ENVIRONMENTAL HEALTH PERSPECTIVES, 1985, 61 (SEP) :21-33

[59]

SMITH DA, 1997, IN PRESS XENOBIOTICA, V27

[60] INVITRO INHIBITION OF 3-METHYLCHOLANTHRENE-INDUCED RAT HEPATIC ARYL-HYDROCARBON HYDROXYLASE BY 8-ACYL-7-HYDROXYCOUMARINS - STRUCTURE-ACTIVITY-RELATIONSHIPS AND METABOLITE PROFILES [J].

STUPANS, I ;

RYAN, AJ .

BIOCHEMICAL PHARMACOLOGY, 1984, 33 (01) :131-139

← 1 2 3 4 5 6 7 →