共 5 条
When is a heme transporter not a heme transporter? When it's a folate transporter
被引:24
作者:

Andrews, Nancy C.
论文数: 0 引用数: 0
h-index: 0
机构: Childrens Hosp, Boston, MA 02115 USA
机构:
[1] Childrens Hosp, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA 02115 USA
关键词:
D O I:
10.1016/j.cmet.2006.12.004
中图分类号:
Q2 [细胞生物学];
学科分类号:
071009 ;
090102 ;
摘要:
Essential nutrients enter the body through a variety of specific transporter molecules expressed in the intestinal epithelium. A recent paper by Qiu et al. (2006) elegantly demonstrates that one of these transporters, previously thought to carry heme, is in fact an important folate transporter.
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页码:5 / 6
页数:2
相关论文
共 5 条
[1]
The kidney in vitamin B12 and folate homeostasis:: characterization of receptors for tubular uptake of vitamins and carrier proteins
[J].
Birn, Henrik
.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY,
2006, 291 (01)
:F22-F36

Birn, Henrik
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Aarhus, Inst Anat, Dept Cell Biol, DK-8000 Aarhus C, Denmark Univ Aarhus, Inst Anat, Dept Cell Biol, DK-8000 Aarhus C, Denmark
[2]
Balancing acts: Molecular control of mammalian iron metabolism
[J].
Hentze, MW
;
Muckenthaler, MU
;
Andrews, NC
.
CELL,
2004, 117 (03)
:285-297

Hentze, MW
论文数: 0 引用数: 0
h-index: 0
机构: Harvard Univ, Sch Med, Childrens Hosp, Boston, MA 02115 USA

Muckenthaler, MU
论文数: 0 引用数: 0
h-index: 0
机构: Harvard Univ, Sch Med, Childrens Hosp, Boston, MA 02115 USA

Andrews, NC
论文数: 0 引用数: 0
h-index: 0
机构: Harvard Univ, Sch Med, Childrens Hosp, Boston, MA 02115 USA
[3]
Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption
[J].
Qiu, Andong
;
Jansen, Michaela
;
Sakaris, Antoinette
;
Min, Sang Hee
;
Chattopadhyay, Shrikanta
;
Tsai, Eugenia
;
Sandoval, Claudio
;
Zhao, Rongbao
;
Akabas, Myles H.
;
Goldman, I. David
.
CELL,
2006, 127 (05)
:917-928

Qiu, Andong
论文数: 0 引用数: 0
h-index: 0
机构: Albert Einstein Coll Med, Dept Med, Bronx, NY 10461 USA

Jansen, Michaela
论文数: 0 引用数: 0
h-index: 0
机构: Albert Einstein Coll Med, Dept Med, Bronx, NY 10461 USA

Sakaris, Antoinette
论文数: 0 引用数: 0
h-index: 0
机构: Albert Einstein Coll Med, Dept Med, Bronx, NY 10461 USA

Min, Sang Hee
论文数: 0 引用数: 0
h-index: 0
机构: Albert Einstein Coll Med, Dept Med, Bronx, NY 10461 USA

Chattopadhyay, Shrikanta
论文数: 0 引用数: 0
h-index: 0
机构: Albert Einstein Coll Med, Dept Med, Bronx, NY 10461 USA

Tsai, Eugenia
论文数: 0 引用数: 0
h-index: 0
机构: Albert Einstein Coll Med, Dept Med, Bronx, NY 10461 USA

Sandoval, Claudio
论文数: 0 引用数: 0
h-index: 0
机构: Albert Einstein Coll Med, Dept Med, Bronx, NY 10461 USA

Zhao, Rongbao
论文数: 0 引用数: 0
h-index: 0
机构: Albert Einstein Coll Med, Dept Med, Bronx, NY 10461 USA

Akabas, Myles H.
论文数: 0 引用数: 0
h-index: 0
机构: Albert Einstein Coll Med, Dept Med, Bronx, NY 10461 USA

Goldman, I. David
论文数: 0 引用数: 0
h-index: 0
机构: Albert Einstein Coll Med, Dept Med, Bronx, NY 10461 USA
[4]
Identification of an intestinal heme transporter
[J].
Shayeghi, M
;
Latunde-Dada, GO
;
Oakhill, JS
;
Laftah, AH
;
Takeuchi, K
;
Halliday, N
;
Khan, Y
;
Warley, A
;
McCann, FE
;
Hider, RC
;
Frazer, DM
;
Anderson, GJ
;
Vulpe, CD
;
Simpson, RJ
;
McKie, AT
.
CELL,
2005, 122 (05)
:789-801

Shayeghi, M
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

Latunde-Dada, GO
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

Oakhill, JS
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

Laftah, AH
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

Takeuchi, K
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

Halliday, N
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

Khan, Y
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

Warley, A
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

McCann, FE
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

Hider, RC
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

Frazer, DM
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

Anderson, GJ
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

Vulpe, CD
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

Simpson, RJ
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England

McKie, AT
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Dept Life Sci, Nutr Sci Res Div, London SE1 9NN, England
[5]
Characterization of a folate transporter in HeLa cells with a low pH optimum and high affinity for pemetrexed distinct from the reduced folate carrier
[J].
Wang, YH
;
Zhao, RB
;
Goldman, ID
.
CLINICAL CANCER RESEARCH,
2004, 10 (18)
:6256-6264

Wang, YH
论文数: 0 引用数: 0
h-index: 0
机构: Yeshiva Univ Albert Einstein Coll Med, Ctr Canc, Bronx, NY 10461 USA

Zhao, RB
论文数: 0 引用数: 0
h-index: 0
机构: Yeshiva Univ Albert Einstein Coll Med, Ctr Canc, Bronx, NY 10461 USA

Goldman, ID
论文数: 0 引用数: 0
h-index: 0
机构: Yeshiva Univ Albert Einstein Coll Med, Ctr Canc, Bronx, NY 10461 USA