Rectifying and Sorting of Regenerating Axons by Free-Standing Nanowire Patterns: A Highway for Nerve Fibers

被引：40

作者：

Hallstrom, Waldemar ^{[1
]}

Prinz, Christelle N. ^{[1
]}

Suyatin, Dmitry ^{[1
]}

Samuelson, Lars ^{[1
]}

Montelius, Lars ^{[1
]}

Kanje, Martin ^{[2
]}

机构：

[1] Lund Univ, Div Solid State Phys, Lund, Sweden

[2] Lund Univ, Dept Cell & Organism Biol, Lund, Sweden

来源：

LANGMUIR | 2009年 / 25卷 / 08期

基金：

瑞典研究理事会;

关键词：

GUIDANCE; SURFACES; CELLS; OUTGROWTH; ALIGNMENT; GROWTH; ARRAYS;

D O I：

10.1021/la900436e

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

We present an EBL-defined nanowire pattern that can sort axons coming from different directions on a substrate. The pattern defines tracks for left-bound traffic and right-bound traffic, which opens up new possibilities for designing neural networks on a chip.

引用

收藏

页码：4343 / 4346

页数：4

相关论文

共 21 条

[1]

The culture of neurons on silicon [J].

Bayliss, SC ;

Buckberry, LD ;

Fletcher, I ;

Tobin, MJ .

SENSORS AND ACTUATORS A-PHYSICAL, 1999, 74 (1-3) :139-142

[2]

PHOSPHORYLATION-DEPENDENT REGULATION OF AXON FASCICULATION [J].

CERVELLO, M ;

LEMMON, V ;

LANDRETH, G ;

RUTISHAUSER, U .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (23) :10548-10552

[3]

Dalby M J, 2005, Eur Cell Mater, V9, P1

[4]

Investigating filopodia sensing using arrays of defined nano-pits down to 35 nm diameter in size [J].

Dalby, MJ ;

Gadegaard, N ;

Riehle, MO ;

Wilkinson, CDW ;

Curtis, ASG .

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2004, 36 (10) :2005-2015

[5]

Topographically modified surfaces affect orientation and growth of hippocampal neurons [J].

Dowell-Mesfin, N. M. ;

Abdul-Karim, M-A ;

Turner, A. M. P. ;

Schanz, S. ;

Craighead, H. G. ;

Roysam, B. ;

Turner, J. N. ;

Shain, W. .

JOURNAL OF NEURAL ENGINEERING, 2004, 1 (02) :78-90

[6]

Neurite guidance on protein micropatterns generated by a piezoelectric microdispenser [J].

Gustavsson, Per ;

Johansson, Fredrik ;

Kanje, Martin ;

Wallman, Lars ;

Linsmeier, Cecilia Eriksson .

BIOMATERIALS, 2007, 28 (06) :1141-1151

[7]

Gallium phosphide nanowires as a substrate for cultured neurons [J].

Hallstrom, Waldemar ;

Martensson, Thomas ;

Prinz, Christelle ;

Gustavsson, Per ;

Montelius, Lars ;

Samuelson, Lars ;

Kanje, Martin .

NANO LETTERS, 2007, 7 (10) :2960-2965

[8]

Axonal outgrowth on nano-imprinted patterns [J].

Johansson, F ;

Carlberg, P ;

Danielsen, N ;

Montelius, L ;

Kanje, M .

BIOMATERIALS, 2006, 27 (08) :1251-1258

[9]

Guidance of neurons on porous patterned silicon: is pore size important? [J].

Johansson, F ;

Kanje, M ;

Eriksson, C ;

Wallman, L .

Physica Status Solidi C - Conferences and Critical Reviews, Vol 2, No 9, 2005, 2 (09) :3258-3262

[10]

Nanomodified surfaces and guidance of nerve cell processes [J].

Johansson, Fredrik ;

Hallstrom, Waldemar ;

Gustavsson, Per ;

Wallman, Lars ;

Prinz, Christelle ;

Montelius, Lars ;

Kanje, Martin .

JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B, 2008, 26 (06) :2558-2561