Does the integrin αA domain act as a ligand for its βA domain?

被引：98

作者：

Alonso, JL

Essafi, M

Xiong, JP

Stehle, T

Arnaout, MA

机构：

[1] Massachusetts Gen Hosp, Renal Unit, Leukocyte Biol & Inflammat Program, Structural Biol Program, Charlestown, MA 02129 USA

[2] Harvard Univ, Sch Med, Charlestown, MA 02129 USA

来源：

CURRENT BIOLOGY | 2002年 / 12卷 / 10期

关键词：

D O I：

10.1016/S0960-9822(02)00852-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

引用

页码：R340 / R342

页数：3

共 20 条

[1]

Cation binding to the integrin CD11b I domain and activation model assessment [J].

Baldwin, ET ;

Sarver, RW ;

Bryant, GL ;

Curry, KA ;

Fairbanks, MB ;

Finzel, BC ;

Garlick, RL ;

Heinrikson, RL ;

Horton, NC ;

Kelley, LLC ;

Mildner, AM ;

Moon, JB ;

Mott, JE ;

Mutchler, VT ;

Tomich, CSC ;

Watenpaugh, KD ;

Wiley, VH .

STRUCTURE, 1998, 6 (07) :923-935

[2]

Antibodies that selectively inhibit leukocyte function-associated antigen 1 binding to intercellular adhesion molecule-3 recognize a unique epitope within the CD11a I domain [J].

Binnerts, ME ;

vanKooyk, Y ;

Edwards, CP ;

Champe, M ;

Presta, L ;

Bodary, SC ;

Figdor, CG ;

Berman, PW .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (17) :9962-9968

[3]

REGULATED EXPRESSION OF MG-2+ BINDING EPITOPE ON LEUKOCYTE INTEGRIN ALPHA-SUBUNITS [J].

DRANSFIELD, I ;

HOGG, N .

EMBO JOURNAL, 1989, 8 (12) :3759-3765

[4]

Structural basis of collagen recognition by integrin α2β1 [J].

Emsley, J ;

Knight, CG ;

Farndale, RW ;

Barnes, MJ ;

Liddington, RC .

CELL, 2000, 101 (01) :47-56

[5]

Identifying the putative metal ion-dependent adhesion site in the beta(2) (CD18) subunit required for alpha(L)beta(2) and alpha(M)beta(2) ligand interactions [J].

Goodman, TG ;

Bajt, ML .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (39) :23729-23736

[6]

Integrin structure [J].

Humphries, MJ .

BIOCHEMICAL SOCIETY TRANSACTIONS, 2000, 28 :311-340

[7]

NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding [J].

Huth, JR ;

Olejniczak, ET ;

Mendoza, R ;

Liang, H ;

Harris, EAS ;

Lupher, ML ;

Wilson, AE ;

Fesik, SW ;

Staunton, DE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (10) :5231-5236

[8]

CRYSTAL-STRUCTURE OF THE A-DOMAIN FROM THE A-SUBUNIT OF INTEGRIN CR3 (CD11B/CD18) [J].

LEE, JO ;

RIEU, P ;

ARNAOUT, MA ;

LIDDINGTON, R .

CELL, 1995, 80 (04) :631-638

[9]

Two conformations of the integrin A-domain (I-domain): A pathway for activation? [J].

Lee, JO ;

Bankston, LA ;

Arnaout, MA ;

Liddington, RC .

STRUCTURE, 1995, 3 (12) :1333-1340

[10]

Two functional states of the CD11b A-domain:: Correlations with key features of two Mn2+-complexed crystal structures [J].

Li, R ;

Rieu, P ;

Griffith, DL ;

Scott, D ;

Arnaout, MA .

JOURNAL OF CELL BIOLOGY, 1998, 143 (06) :1523-1534

← 1 2 →