Multiple sclerosis-associated retrovirus and MS prognosis - An observational study

被引：64

作者：

Sotgiu, S

Serra, C

Mameli, G

Pugliatti, M

Rosati, G

Arru, G

Dolei, A

机构：

[1] Univ Sassari, Ist Clin Neurol, I-07100 Sassari, Italy

[2] Univ Sassari, Microbiol Sect, Dept Biomed Sci, I-07100 Sassari, Italy

来源：

NEUROLOGY | 2002年 / 59卷 / 07期

关键词：

D O I：

10.1212/WNL.59.7.1071

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

MS-associated retrovirus (MSRV) in the CSF may have gliotoxic properties and could be associated with a more disabling MS. The authors tested this hypothesis in 15 untreated patients with MS: 6 MSRV- and 9 MSRV+ at the time of CSF withdrawal. After a 3-year mean follow-up, MSRV- patients showed a stable MS course, whereas MSRV+ patients had a progressive course (p = 0.01).

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页码：1071 / 1073

页数：3

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