A ring-closing metathesis-mediated route to novel enantiopure conformationally restricted cyclic amino acids

被引：45

作者：

Tjen, KCMF

Kinderman, SS

Schoemaker, HE

Hiemstra, H

Rutjes, FPJT

机构：

[1] Univ Amsterdam, Inst Mol Chem, NL-1018 WS Amsterdam, Netherlands

[2] DSM Res BV, Dept Organ Chem & Biotechnol, NL-6160 MD Geleen, Netherlands

[3] Univ Nijmegen, Dept Organ Chem, NL-6525 ED Nijmegen, Netherlands

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 08期

关键词：

D O I：

10.1039/b001253j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A combination of palladium-catalysed N,O-acetal formation, ruthenium-catalysed ring-closing metathesis and N-sulfonyliminium ion-mediated C-C bond formation constitutes an efficient and versatile route to a set of enantiomerically pure 2,6-disubstituted unsaturated pipecolic acid derivatives.

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收藏

页码：699 / 700

页数：2

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