Multivalent neoglycoconjugates: solid-phase synthesis of N-linked alpha-sialodendrimers

被引:37
作者
Llinares, M [1 ]
Roy, R [1 ]
机构
[1] UNIV OTTAWA,DEPT CHEM,OTTAWA,ON K1N 6N5,CANADA
关键词
D O I
10.1039/a703679e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of N-linked alpha-sialodendrimers with valencies of 2, 4 and 8 has been scaffolded on an N,N-bis(3-aminopropyl)succinamic acid core using Wang resin and 9-fluorenylmethoxycarbonyl and 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate solid-phase chemistry.
引用
收藏
页码:2119 / 2120
页数:2
相关论文
共 18 条
[11]  
ROY R, 1996, POLYM NEWS, V21, P226
[13]  
TOMALIA DA, 1993, TOP CURR CHEM, V165, P193
[14]   STRUCTURE AND ENERGETICS OF PROTEIN CARBOHYDRATE COMPLEXES [J].
TOONE, EJ .
CURRENT OPINION IN STRUCTURAL BIOLOGY, 1994, 4 (05) :719-728
[15]  
TROPPER FD, 1992, SYNTHESIS-STUTTGART, P618
[16]   Novel dendritic alpha-sialosides: Synthesis of glycodendrimers based on a 3,3'-iminobis(propylamine) core [J].
Zanini, D ;
Roy, R .
JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (21) :7348-7354
[17]   Synthesis of new alpha-thiosialodendrimers and their binding properties to the sialic acid specific lectin from Limax flavus [J].
Zanini, D ;
Roy, R .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (09) :2088-2095
[18]   Self-assembling dendrimers [J].
Zimmerman, SC ;
Zeng, FW ;
Reichert, DEC ;
Kolotuchin, SV .
SCIENCE, 1996, 271 (5252) :1095-1098