Selenium-directed conjugate addition of amines to dimethyl 2-phenylseleno fumarate: Regio and diastereoselective synthesis of 2-phenylseleno-3-amino succinates

被引：12

作者：

Bella, M

DOnofrio, F

Margarita, R

Parlanti, L

Piancatelli, G

Mangoni, A

机构：

[1] UNIV ROMA LA SAPIENZA,IST NAZL COORDINAMENTO CHIM SISTEMI BIOL,CTR CNR CHIM SOSTANZE ORGAN NAT,I-00185 ROME,ITALY

[2] UNIV ROMA LA SAPIENZA,IST NAZL COORDINAMENTO CHIM SISTEMI BIOL,DIPARTIMENTO CHIM,I-00185 ROME,ITALY

[3] UNIV NAPLES FEDERICO II,DIPARTIMENTO CHIM SOSTANZE ORGAN NAT,I-80131 NAPLES,ITALY

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 45期

关键词：

D O I：

10.1016/S0040-4039(97)10046-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Dimethyl 2-phenylseleno fumarate 1 acts as a strong Michael acceptor of amines, providing the corresponding 2-phenylseleno-3-amino succinates 2a and 2b in very high yields with complete regio-and good diastereoselectivity. (C) 1997 Elsevier Science Ltd.

引用

页码：7917 / 7918

页数：2

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