Innate and acquired immunity in atherogenesis

被引：537

作者：

Binder, CJ ^{[1
]}

Chang, MK ^{[1
]}

Shaw, PX ^{[1
]}

Miller, YI ^{[1
]}

Hartvigsen, K ^{[1
]}

Dewan, A ^{[1
]}

Witztum, JL ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Med, La Jolla, CA 92093 USA

来源：

NATURE MEDICINE | 2002年 / 8卷 / 11期

关键词：

D O I：

10.1038/nm1102-1218

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Traditional risk factors like hypercholesterolemia are important for atherogenesis, but it is now apparent that the immune system also plays an important role. Uncovering the mechanisms by which specific components of the immune system impact atherogenesis will not only provide new insights into the pathogenesis of lesion formation, but could also lead to novel therapeutic approaches that involve immune modulation.

引用

页码：1218 / 1226

页数：9

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