Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody

被引：310

作者：

Gleghorn, Jason P. ^{[1
]}

Pratt, Erica D. ^{[2
]}

Denning, Denise ^{[3
]}

Liu, He ^{[4
]}

Bander, Neil H. ^{[4
]}

Tagawa, Scott T. ^{[5
]}

Nanus, David M. ^{[5
]}

Giannakakou, Paraskevi A. ^{[5
]}

Kirby, Brian J. ^{[1
]}

机构：

[1] Cornell Univ, Sibley Sch Mech & Aerosp Engn, Coll Engn, Ithaca, NY 14853 USA

[2] Cornell Univ, Dept Biomed Engn, Coll Engn, Ithaca, NY 14853 USA

[3] Dublin City Univ, Dept Phys Sci, Dublin 9, Ireland

[4] Cornell Univ, Weill Cornell Med Coll, Dept Urol, New York, NY 10065 USA

[5] Cornell Univ, Weill Cornell Med Coll, Div Hematol, New York, NY 10065 USA

来源：

LAB ON A CHIP | 2010年 / 10卷 / 01期

基金：

美国国家科学基金会;

关键词：

PARTICLE SEPARATION;

D O I：

10.1039/b917959c

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Geometrically enhanced differential immunocapture (GEDI) and an antibody for prostate-specific membrane antigen (PSMA) are used for high-efficiency and high-purity capture of prostate circulating tumor cells from peripheral whole blood samples of castrate-resistant prostate cancer patients.

引用

页码：27 / 29

页数：3

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