Matrix-assisted laser desorption/ionization mass spectrometry of synthetic polymers. 4. Coupling of size exclusion chromatography and MALDI-TOF using a spray-deposition interface

被引：31

作者：

Esser, E ^{[1
]}

Keil, C ^{[1
]}

Braun, D ^{[1
]}

Montag, P ^{[1
]}

Pasch, H ^{[1
]}

机构：

[1] Deutsch Kunststoff Inst Darmstadt, D-64289 Darmstadt, Germany

来源：

POLYMER | 2000年 / 41卷 / 11期

关键词：

MALDI-TOF mass spectrometry; size exclusion chromtography; hyphenated techniques;

D O I：

10.1016/S0032-3861(99)00646-1

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Size exclusion chromatography and MALDI-TOF mass spectrometry can be effectively coupled via a robotic interface, where chromatographic fractions are sprayed directly onto a moving MALDI-TOF target through a heated capillary nozzle. The target is precoated with an appropriate matrix, such as dithranol. For polydisperse synthetic polymers a continuous track of matter is deposited onto the matrix surface. After deposition of the sample fractions, the MALDI-TOF target is introduced into the spectrometer, and spectra are taken from different positions of the polymer track. As a result, well-resolved spectra are obtained which are characteristic for different molar mass fractions of the sample. In the case of copolymers, information on molar mass and copolymer composition is accessible. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：4039 / 4046

页数：8