Food allergies: Prevalence, molecular characterization, and treatment/prevention strategies

被引:56
作者
Lee, Laurie A. [1 ]
Burks, A. Wesley [1 ]
机构
[1] Duke Univ, Med Ctr, Durham, NC 27710 USA
关键词
food challenge; skin-prick test; elimination diet; immunotherapy; oral tolerance;
D O I
10.1146/annurev.nutr.26.061505.111211
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
A significant proportion of the population is either affected by or concerned about food allergy. Our knowledge about food allergens and how they stimulate the immune system has increased dramatically over the past decade. However, reasons for the increased prevalence of food allergy are not clear. The diagnosis of food allergy requires that the patient and caregivers examine all foods for the presence of potential allergens in order to prevent inadvertent ingestion and further reactions. Fortunately, many children develop tolerance to allergenic foods after a period of dietary elimination. Various immunotherapy approaches are under investigation to alleviate or prevent food-induced reactions in those who have persistent food allergies.
引用
收藏
页码:539 / 565
页数:27
相关论文
共 128 条
[92]  
Sampson HA, 2001, J ALLERGY CLIN IMMUN, V107, P891, DOI 10.1067/mai.2001.114708
[93]   FATAL AND NEAR-FATAL ANAPHYLACTIC REACTIONS TO FOOD IN CHILDREN AND ADOLESCENTS [J].
SAMPSON, HA ;
MENDELSON, L ;
ROSEN, JP .
NEW ENGLAND JOURNAL OF MEDICINE, 1992, 327 (06) :380-384
[94]   Summary and recommendations: Classification of gastrointestinal manifestations due to immunologic reactions to foods in infants and young children [J].
Sampson, HA ;
Anderson, JA .
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2000, 30 :S87-S94
[95]   SPONTANEOUS RELEASE OF HISTAMINE FROM BASOPHILS AND HISTAMINE-RELEASING FACTOR IN PATIENTS WITH ATOPIC-DERMATITIS AND FOOD HYPERSENSITIVITY [J].
SAMPSON, HA ;
BROADBENT, KR ;
BERNHISELBROADBENT, J .
NEW ENGLAND JOURNAL OF MEDICINE, 1989, 321 (04) :228-232
[96]   Food allergy. Part 1: Immunopathogenesis and clinical disorders [J].
Sampson, HA .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1999, 103 (05) :717-728
[97]   Update on food allergy [J].
Sampson, HA .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2004, 113 (05) :805-819
[98]   Differences in antigen-specific T-cell responses between infants with atopic dermatitis with and without cow's milk allergy:: Relevance of TH2 cytokines [J].
Schade, RP ;
Van Ieperen-Van Dijk, AG ;
Van Reijsen, FC ;
Versluis, C ;
Kimpen, JLL ;
Knol, EF ;
Bruijnzeel-Koomen, CAFM ;
Van Hoffen, E .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2000, 106 (06) :1155-1162
[99]  
Schloss OM, 1912, AM J DIS CHILD, V3, P341
[100]   Food allergy in children [J].
Scurlock, AM ;
Lee, LA ;
Burks, AW .
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA, 2005, 25 (02) :369-+