Synthesis of glycopolymers containing GM(3)-saccharide

被引：27

作者：

Cao, SD ^{[1
]}

Roy, R ^{[1
]}

机构：

[1] UNIV OTTAWA,DEPT CHEM,OTTAWA,ON K1N 6N5,CANADA

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 20期

关键词：

D O I：

10.1016/0040-4039(96)00584-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

GM(3)-trisaccharide [Neu5Ac alpha-(2-->3)-Gal beta-(1-->4)-Glc beta-(1-->OR)] was synthesized using our ''active-latent'' thioglycosylation strategy. The trisaccharide was prepared with a p-acrylamidophenyl aglycon for copolymerization with acrylamide. The resulting water-soluble sialyl alpha-(2-->3)-lactoside copolyacrylamide with different carbohydrate incorporation was shown to possess antigenic properties. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：3421 / 3424

页数：4

共 21 条

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