Management of detrusor-external sphincter dyssynergia

被引：32

作者：

Ahmed, Hashim U. ^{[1
]}

Shergill, Iqbal S. ^{[1
]}

Arya, Manit ^{[1
]}

Shah, P. Julian R. ^{[1
]}

机构：

[1] UCL, Inst Urol & Nephrol, London W1W 7EY, England

来源：

NATURE CLINICAL PRACTICE UROLOGY | 2006年 / 3卷 / 07期

关键词：

botulinum toxin; detrusor-external sphincter dyssynergia; external sphincterotomy; management; spinal cord injury;

D O I：

10.1038/ncpuro0521

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Detrusor-external sphincter dyssynergia (DSD) is a debilitating problem in patients with spinal cord injury. DSD carries a high risk of complications, and even life expectancy can be affected. The mainstay of treatment is the use of antimuscarinic medication and catheterization, but in those for whom this is not possible external sphincterotomy has been the traditional management route. External sphincterotomy, however, is associated with significant risks, including hemorrhage, erectile dysfunction and the need for repeat procedures, and over the last decade alternatives have been investigated, such as urethral stents and botulinum toxin injection. We present a review of DSD, including the current management strategies and prospects for future treatment.

引用

页码：368 / 380

页数：13

共 64 条

[51] Botulinum A toxin as a treatment of detrusor-sphincter dyssynergia in patients with spinal cord injury: MRI controlled transperineal injections [J].