Labelling of [Leu5]-enkephalin with organometallic Mo complexes by solid-phase synthesis

被引：55

作者：

van Staveren, DR

Metzler-Nolte, N

机构：

[1] Heidelberg Univ, Inst Pharmazeut Chem, D-69120 Heidelberg, Germany

[2] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 13期

关键词：

D O I：

10.1039/b203128k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The neuropeptide leucine-enkephalin ([Leu(5)]-enkephalin) has been covalently labelled with the two organometallic Mo carbonyl complexes Mo(R-His)(allyl)(CO)(2) (His = N-delta,N,O-L- histidinate) and Mo(R-bpa)(CO)(3) (bpa = bis(2-picolyl) amine) on the resin as the last step of a solid-phase synthesis scheme and in solution.

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页码：1406 / 1407

页数：2

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