To live or die by the sword: The regulation of apoptosis by the proteasome

被引:31
作者
Friedman, J [1 ]
Xue, D [1 ]
机构
[1] Univ Colorado, Dept Mol Cellular & Dev Biol, Boulder, CO 80309 USA
关键词
D O I
10.1016/S1534-5807(04)00104-2
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The proteasome has been implicated in the control of apoptosis by modulating the levels of both pro- and antiapoptotic molecules. A recent study published in the April 9th issue of Molecular Cell reveals that caspase-dependent inactivation of the proteasome can amplify the activation of apoptosis.
引用
收藏
页码:460 / 461
页数:2
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