Modulation of insulin signaling in human skeletal muscle in response to exercise

被引:21
作者
Kirwan, JP
Jing, M
机构
[1] Case Western Reserve Univ, Sch Med, Metrohlth Med Ctr, Dept Reprod Biol, Cleveland, OH 44109 USA
[2] Case Western Reserve Univ, Sch Med, Metrohlth Med Ctr, Dept Nutr, Cleveland, OH 44109 USA
来源
EXERCISE AND SPORT SCIENCES REVIEWS | 2002年 / 30卷 / 02期
关键词
insulin sensitivity; signal transduction; exercise training; PI; 3-kinase; TNF-alpha;
D O I
10.1097/00003677-200204000-00008
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
KIRWAN, J.P., and M. JING. Modulation of insulin signaling in human skeletal muscle in response to exercise. Exerc. Sport Sci. Rev., Vol. 30, No. 2, pp. 85-90, 2002. Exercise is widely recommended for the treatment of obesity, insulin resistance, and type II diabetes mellitus. Recent discoveries in the molecular and cellular regulation of insulin-mediated glucose metabolism in skeletal muscle have provided a deeper understanding of how exercise modulates insulin action.
引用
收藏
页码:85 / 90
页数:6
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