RNA interference - A new weapon against HIV and beyond

被引：50

作者：

Kitabwalla, M ^{[1
]}

Ruprecht, RM ^{[1
]}

机构：

[1] Dana Farber Canc Inst, Boston, MA 02115 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2002年 / 347卷 / 17期

关键词：

D O I：

10.1056/NEJMcibr022294

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：1364 / 1367

页数：4

共 25 条

[1] Role for a bidentate ribonuclease in the initiation step of RNA interference [J].

Bernstein, E ;

Caudy, AA ;

Hammond, SM ;

Hannon, GJ .

NATURE, 2001, 409 (6818) :363-366

[2] Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses [J].

Bitko V. ;

Barik S. .

BMC Microbiology, 1 (1) :1-11

[3] A system for stable expression of short interfering RNAs in mammalian cells [J].

Brummelkamp, TR ;

Bernards, R ;

Agami, R .

SCIENCE, 2002, 296 (5567) :550-553

[4] Replication of the human hepatitis delta virus genome is initiated in mouse hepatocytes following intravenous injection of naked DNA or RNA sequences [J].

Chang, JH ;

Sigal, LJ ;

Lerro, A ;

Taylor, J .

JOURNAL OF VIROLOGY, 2001, 75 (07) :3469-3473

[5]

Dornburg R, 2000, Adv Pharmacol, V49, P229

[6] RNA interference is mediated by 21-and 22-nucleotide RNAs [J].

Elbashir, SM ;

Lendeckel, W ;

Tuschl, T .

GENES & DEVELOPMENT, 2001, 15 (02) :188-200

[7] Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells [J].

Elbashir, SM ;

Harborth, J ;

Lendeckel, W ;

Yalcin, A ;

Weber, K ;

Tuschl, T .

NATURE, 2001, 411 (6836) :494-498

[8] Short interfering RNA confers intracellular antiviral immunity in human cells [J].

Gitlin, L ;

Karelsky, S ;

Andino, R .

NATURE, 2002, 418 (6896) :430-434

[9] RNA interference [J].

Hannon, GJ .

NATURE, 2002, 418 (6894) :244-251

[10] Modulation of HIV-1 replication by RNA interference [J].

Jacque, JM ;

Triques, K ;

Stevenson, M .

NATURE, 2002, 418 (6896) :435-438

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