Cytochalasins and phytotoxins from the fungus Xylaria obovata

被引：67

作者：

Abate, D

Abraham, WR

Meyer, H

机构：

[1] GESELL BIOTECHNOL FORSCH MBH,DEPT MICROBIOL,D-38124 BRAUNSCHWEIG,GERMANY

[2] UNIV ADDIS ABABA,DEPT BIOL,ADDIS ABABA,ETHIOPIA

来源：

PHYTOCHEMISTRY | 1997年 / 44卷 / 08期

关键词：

Xylaria obovata; ascomycotina; cytochalasins; xylobovatin; clonostachydiol; xylobovide; phaseolinon; phytotoxin;

D O I：

10.1016/S0031-9422(96)00780-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The new metabolites xylobovatin, 19,20-epoxycytochalasin C, deacetyl-19,20-epoxy-cytochalasin C, xylobovide and 4,6,10,12-tridecatetraene-2,8-diol, and the known clonostachydiol and phaseolinon were isolated from the culture broth of the Ethiopian fungus Xylaria obovata. While the cytochalasins are cytotoxins, clonostachydiol is an anthelmintic, and phaseolinon and xylobovide show phytotoxic effects. The formation of these metabolites was studied and the more oxidized cytochalasins were found to be formed late in the fermentation process on moist sterile rice. Copyright (C) 1997 Elsevier Science Ltd.

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页码：1443 / 1448

页数：6

相关论文

共 15 条

[1] FUSOXYSPORONE - A NEW TYPE OF DITERPENE FROM FUSARIUM-OXYSPORUM [J].

ABRAHAM, WR ;

HANSSEN, HP .

TETRAHEDRON, 1992, 48 (48) :10559-10562

[2] 2 NEW MOULD METABOLITES RELATED TO AVENACIOLIDE [J].

ALDRIDGE, DC ;

TURNER, WB .

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1971, (13) :2431-&

[3] METABOLITES OF THE HIGHER FUNGI .23. THE PUNCTAPORONINS - NOVEL BI-CYCLIC, TRI-CYCLIC, AND TETRA-CYCLIC SESQUITERPENES RELATED TO CARYOPHYLLENE, FROM THE FUNGUS PORONIA-PUNCTATA (LINNAEUS, FRIES) FRIES [J].

ANDERSON, JR ;

EDWARDS, RL ;

POYSER, JP ;

WHALLEY, AJS .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1988, (04) :823-831

[4] 2 NEW CYTOTOXIC CYTOCHALASINS FROM XYLARIA-OBOVATA [J].

DAGNE, E ;

GUNATILAKA, AAL ;

ASMELLASH, S ;

ABATE, D ;

KINGSTON, DGI ;

HOFMANN, GA ;

JOHNSON, RK .

TETRAHEDRON, 1994, 50 (19) :5615-5620

[5]

DONG D, 1992, TIANRAN CHANWU YANJI, V4, P44

[6] SECONDARY METABOLITES BY CHEMICAL-SCREENING .21. CLONOSTACHYDIOL, A NOVEL ANTHELMINTIC MACRODIOLIDE FROM THE FUNGUS CLONOSTACHYS-CYLINDROSPORA (STRAIN FH-A-6607) [J].

GRABLEY, S ;

HAMMANN, P ;

THIERICKE, R ;

WINK, J ;

PHILIPPS, S ;

ZEECK, A .

JOURNAL OF ANTIBIOTICS, 1993, 46 (02) :343-345

[7] CYTO-TOXIC STEROIDS FROM THE MUSHROOM AGARICUS-BLAZEI [J].

KAWAGISHI, H ;

KATSUMI, R ;

SAZAWA, T ;

MIZUNO, T ;

HAGIWARA, T ;

NAKAMURA, T .

PHYTOCHEMISTRY, 1988, 27 (09) :2777-2779

[8] BIOLOGICALLY-ACTIVE METABOLITES FROM FUNGI .3. SPOROTHRIOLIDE-DISCOSIOLIDE, AND 4-EPI-ETHISOLIDE - NEW FUROFURANDIONES FROM SPOROTHRIX SP, DISCOSIA SP, AND PEZICULA-LIVIDA [J].

KROHN, K ;

LUDEWIG, K ;

AUST, HJ ;

DRAEGER, S ;

SCHULZ, B .

JOURNAL OF ANTIBIOTICS, 1994, 47 (01) :113-118

[9] STUDIES ON METABOLITES OF ZYGOSPORIUM-MASONII .2. STRUCTURES OF ZYGOSPORINS D, E, F, AND G [J].

MINATO, H ;

KATAYAMA, T .

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1970, (01) :45-+

[10]

RAO AVR, 1995, TETRAHEDRON LETT, V36, P143