Selfassembly of metallic nanoparticle arrays by DNA scaffolding

被引:130
作者
Xiao, SJ
Liu, FR
Rosen, AE
Hainfeld, JF
Seeman, NC
Musier-Forsyth, K
Kiehl, RA [1 ]
机构
[1] Univ Minnesota, Dept Elect & Comp Engn, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA
[3] NYU, Dept Chem, New York, NY 10003 USA
[4] Brookhaven Natl Lab, Dept Biol, Upton, NY 11973 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
nanoparticles; DNA; nanotechnology; self-assembly; nanoelectronics;
D O I
10.1023/A:1021145208328
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report the self-assembly of metallic nanoparticle arrays using DNA crystals as a programmable molecular scaffolding. Gold nanoparticles, 1.4 nm in diameter, are assembled in two-dimensional arrays with interparticle spacings of 4 and 64 nm. The nanoparticles form precisely integrated components, which are covalently bonded to the DNA scaffolding. These results show that heterologous chemical systems can be assembled into precise, programmable geometrical arrangements by DNA scaffolding, thereby representing a critical step toward the realization of DNA nanotechnology.
引用
收藏
页码:313 / 317
页数:5
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