Hydrophilic elastomeric biomaterials based on resilin-like polypeptides

被引：105

作者：

Charati, Manoj B. ^{[1
]}

Ifkovits, Jamie L. ^{[2
]}

Burdick, Jason A. ^{[2
]}

Linhardt, Jeffery G. ^{[3
]}

Kiick, Kristi L. ^{[1
]}

机构：

[1] Univ Delaware, Dept Mat Sci & Engn, Newark, DE 19716 USA

[2] Univ Penn, Dept Bioengn, Philadelphia, PA 19104 USA

[3] Bausch & Lomb Inc, Rochester, NY 14609 USA

来源：

SOFT MATTER | 2009年 / 5卷 / 18期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

RUBBER-LIKE PROTEIN; TISSUE-REPAIR; MECHANICAL-PROPERTIES; EXTRACELLULAR-MATRIX; CONTROLLED-RELEASE; BLOCK-COPOLYMERS; INSECT CUTICLE; CELL; HYDROGELS; HYDROPHOBICITY;

D O I：

10.1039/b910980c

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The production of complex, yet well defined materials offers many opportunities in regenerative medicine, in which the mechanical and biological properties of the matrix must meet stringent requirements. Here we report the recombinant production of modular polypeptidic materials, based on the highly resilient protein resilin, which are equipped with multiple biologically active domains. The recombinant materials exhibit useful mechanical and cell adhesion behavior.

引用

页码：3412 / 3416

页数：5

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