A novel FeS cluster in Fe-only hydrogenases

被引:353
作者
Nicolet, Y
Lemon, BJ
Fontecilla-Camps, JC
Peters, JW
机构
[1] CEA, CNRS, Inst Biol Struct Jean Pierre Ebel, Cristallog & Cristallogenese Prot Lab, F-38027 Grenoble 1, France
[2] Utah State Univ, Dept Chem & Biochem, Logan, UT 84322 USA
关键词
D O I
10.1016/S0968-0004(99)01536-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Many microorganisms can use molecular hydrogen as a source of electrons or generate it by reducing protons. These reactions are catalysed by metalloenzymes of two types: NiFe and Fe-only hydrogenases. Here, we review recent structural results concerning the latter, putting special emphasis on the characteristics of the active site.
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页码:138 / 143
页数:6
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