New perch for the winged helix

被引:20
作者
Wolberger, C
Campbell, R
机构
[1] Johns Hopkins Univ, Sch Med, Dept Biophys & Biophys Chem, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Sch Med, Howard Hughes Med Inst, Baltimore, MD 21205 USA
关键词
D O I
10.1038/74004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The human transcription factor RFX1, is found to belong to the winged-helix family of DNA binding proteins, despite an absence of significant sequence similarity. Even more surprising is the Very different mode of DNA binding as compared with previously characterized winged-helix proteins that bind to B-form DNA.
引用
收藏
页码:261 / 262
页数:2
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