AutoGRAPH:: an interactive web server for automating and visualizing comparative genome maps

被引:44
作者
Derrien, Thomas [1 ]
Andre, Catherine [1 ]
Galibert, Francis [1 ]
Hitte, Christophe [1 ]
机构
[1] Univ Rennes 1, CNRS UMR Genet & Dev 6061, IFR 140, F-35043 Rennes, France
关键词
D O I
10.1093/bioinformatics/btl618
中图分类号
Q5 [生物化学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
AutoGRAPH is an interactive web server for automatic multi-species comparative genomics analyses based on personal datasets or pre-inserted public datasets. This program automatically identifies conserved segments (CS) and breakpoint regions, assesses the conservation of marker/gene order between organisms, constructs synteny maps for two to three species and generates high-quality, interactive displays facilitating the identification of chromosomal rearrangements. AutoGRAPH can also be used for the integration and comparison of several types of genomic resources (meiotic maps, radiation hybrid maps and genome sequences) for a single species, making AutoGRAPH a versatile tool for comparative genomics analysis.
引用
收藏
页码:498 / 499
页数:2
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