Reference based annotation with GeneMapper

被引:61
作者
Chatterji, Sourav [1 ]
Pachter, Lior
机构
[1] Univ Calif Berkeley, Dept Comp Sci, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Dept Math, Berkeley, CA 94720 USA
关键词
D O I
10.1186/gb-2006-7-4-r29
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
We introduce GeneMapper, a program for transferring annotations from a well annotated genome to other genomes. Drawing on high quality curated annotations, GeneMapper enables rapid and accurate annotation of newly sequenced genomes and is suitable for both finished and draft genomes. GeneMapper uses a profile based approach for mapping genes into multiple species, improving upon the standard pairwise approach. GeneMapper is freely available for academic use.
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页数:10
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