Reference based annotation with GeneMapper

被引:61
作者
Chatterji, Sourav [1 ]
Pachter, Lior
机构
[1] Univ Calif Berkeley, Dept Comp Sci, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Dept Math, Berkeley, CA 94720 USA
关键词
D O I
10.1186/gb-2006-7-4-r29
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
We introduce GeneMapper, a program for transferring annotations from a well annotated genome to other genomes. Drawing on high quality curated annotations, GeneMapper enables rapid and accurate annotation of newly sequenced genomes and is suitable for both finished and draft genomes. GeneMapper uses a profile based approach for mapping genes into multiple species, improving upon the standard pairwise approach. GeneMapper is freely available for academic use.
引用
收藏
页数:10
相关论文
共 38 条
[21]  
Gross SS, 2005, LECT NOTES COMPUT SC, V3500, P374
[22]   AMINO-ACID SUBSTITUTION MATRICES FROM PROTEIN BLOCKS [J].
HENIKOFF, S ;
HENIKOFF, JG .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (22) :10915-10919
[23]  
Huang X, 1996, Microb Comp Genomics, V1, P281
[24]   The UCSC Genome Browser Database [J].
Karolchik, D ;
Baertsch, R ;
Diekhans, M ;
Furey, TS ;
Hinrichs, A ;
Lu, YT ;
Roskin, KM ;
Schwartz, M ;
Sugnet, CW ;
Thomas, DJ ;
Weber, RJ ;
Haussler, D ;
Kent, WJ .
NUCLEIC ACIDS RESEARCH, 2003, 31 (01) :51-54
[25]   Eval: A software package for analysis of genome annotations [J].
Keibler, E ;
Brent, MR .
BMC BIOINFORMATICS, 2003, 4 (1)
[26]  
Kent WJ, 2002, GENOME RES, V12, P656, DOI [10.1101/gr.229202, 10.1101/gr.229202. Article published online before March 2002]
[27]   ECgene: Genome-based EST clustering and gene modeling for alternative splicing [J].
Kim, N ;
Shin, S ;
Lee, S .
GENOME RESEARCH, 2005, 15 (04) :566-576
[28]  
Kulp D, 1996, Proc Int Conf Intell Syst Mol Biol, V4, P134
[29]   Multiple-sequence functional annotation and the generalized hidden Markov phylogeny [J].
McAuliffe, JD ;
Pachter, L ;
Jordan, MI .
BIOINFORMATICS, 2004, 20 (12) :1850-1860
[30]   Gene structure conservation aids similarity based gene prediction [J].
Meyer, IM ;
Durbin, R .
NUCLEIC ACIDS RESEARCH, 2004, 32 (02) :776-783