Immunomodulatory and antimicrobial effects of some traditional Chinese medicinal herbs: A review

被引：265

作者：

Tan, BKH ^{[1
]}

Vanitha, J ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Pharmacol, Fac Med, Singapore 117597, Singapore

来源：

CURRENT MEDICINAL CHEMISTRY | 2004年 / 11卷 / 11期

关键词：

anti-bacterial; anti-fungal; anti-microbial; Chinese herbs; immune system; phytochemicals; TCM; herbal toxicology;

D O I：

10.2174/0929867043365161

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The current practice of ingesting phytochemicals to support the immune system or to fight infections is based on centuries-old tradition. We review reports on seven Chinese herbs, (Aloe vera Mill. (Aloaceae), Angelica species (Umbelliferae), Astragalus membranaceus Bunge. (Leguminosae), Ganoderma lucidum (Fr.) Karst. (Ganodermataceae), Panax ginseng C.A Mey. (Araliaceae), Scutellaria species (Lamiaceae) and Zingiber officinale Rose. (Zingiberaccae) with emphasis to their immunomodulatory and antimicrobial activities. While some of these herbaceous plants have a direct inhibitory effect on microbial organisms, we observe that each plant has at least one compound that selectively modulates cells of the immune system. The successful derivation of pure bioactive compounds from Ganoderma lucidum, ginseng and Zingiber officinale supports the traditional practice of using these plants to stimulate the immune system. As many modern drugs are often patterned after phytochemicals, studying the influence of each compound on immune cells as well as microbes can provide useful insights to the development of potentially useful new pharmacological agents.

引用

页码：1423 / 1430

页数：8