Cardiac mitochondrial dysfunction in Leigh syndrome

被引：12

作者：

MarinGarcia, J

Ananthakrishnan, R

Korson, M

Goldenthal, MJ

PerezAtayde, A

机构：

[1] ST BARNABAS HOSP,LIVINGSTON,NJ 07039

[2] HARVARD UNIV,SCH MED,CHILDRENS HOSP,BOSTON,MA 02115

来源：

PEDIATRIC CARDIOLOGY | 1996年 / 17卷 / 06期

关键词：

Leigh syndrome; cardiomyopathy; mitochondrial disease;

D O I：

10.1007/s002469900084

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

An infant with Leigh syndrome and associated cardiomyopathy is described. Abnormal activities of mitochondrial respiratory complexes III and V and a change in mtDNA at nt 8993 were detected in heart and skeletal muscle but not in liver.

引用

页码：387 / 389

页数：3