Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy

被引:185
作者
Greene, WC [1 ]
Peterlin, BM
机构
[1] Univ Calif San Francisco, Gladstone Inst Virol & Immunol, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Rosalind Russell Med Res Ctr, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Dept Med, San Francisco, CA USA
[4] Univ Calif San Francisco, Dept Microbiol, San Francisco, CA 94143 USA
[5] Univ Calif San Francisco, Dept Immunol, San Francisco, CA 94143 USA
关键词
D O I
10.1038/nm0702-673
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Adequate control of HIV requires impairing the infection, replication and spread of the virus, no small task given the extraordinary capacity of HIV to exploit the cell's molecular machinery in the course of infection. Understanding the dynamic interplay of host cell and virus is essential to the effort to eradicate HIV.
引用
收藏
页码:673 / 680
页数:8
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