Seven new polyacetylene derivatives, showing both potent metamorphosis-inducing activity in ascidian larvae and antifouling activity against barnacle larvae, from the marine sponge Callyspongia truncata

被引：72

作者：

Tsukamoto, S ^{[1
]}

Kato, H ^{[1
]}

Hirota, H ^{[1
]}

Fusetani, N ^{[1
]}

机构：

[1] RES DEV CORP JAPAN,ERATO,FUSETANI BIOFOULING PROJECT,NIIGATA ENGN CO LTD,ISOGO KU,YOKOHAMA,KANAGAWA 235,JAPAN

来源：

JOURNAL OF NATURAL PRODUCTS | 1997年 / 60卷 / 02期

关键词：

D O I：

10.1021/np9606097

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Seven new polyacetylene derivatives, two hydrocarbons (callytetrayne and callypentayne) and five triols (callytriols A-E), were isolated from the marine sponge Callyspongia truncata along with the known siphonodiol and its monosulfates and disulfates. All compounds showed potent metamorphosis-inducing activity in the ascidian Halocynthia roretzi larvae, with ED(100) values of 0.13-1.3 mu g/mL, and the triols also showed antifouling activity against the barnacle Balanus amphitrite larvae, with ED(50) values of 0.24-4.5 mu g/mL.

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页码：126 / 130

页数：5

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