The efficacy of thermotherapy to treat cutaneous leishmaniasis in Colombia: a comparative observational study in an operational setting

被引：18

作者：

Carlos Vega, Juan ^{[1
,2
]}

Fernando Sanchez, Boris ^{[3
]}

Mery Montero, Luz ^{[3
]}

Montana, Rafael ^{[3
]}

del Pilar Mahecha, Mercedes ^{[3
]}

Duenes, Bladimir ^{[3
]}

Rocio Baron, Angela ^{[3
]}

Reithinger, Richard ^{[4
,5
]}

机构：

[1] Univ Mil Nueva Granada, Bogota, Colombia

[2] Univ Bosque, Bogota, Colombia

[3] Hosp San Juan Bautista, Chaparral, Tolima, Colombia

[4] London Sch Hyg & Trop Med, London WC1, England

[5] George Washington Univ, Sch Med & Hlth Sci, Washington, DC 20052 USA

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2009年 / 103卷 / 07期

关键词：

Leishmaniasis; Treatment; Thermotherapy; Meglumine antimoniate; Prevention and control; Colombia; PENTAMIDINE; GLUCANTIME; HEAT;

D O I：

10.1016/j.trstmh.2008.10.039

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

An open label, comparative study to compare the efficacy of thermotherapy to meglumine antimoniate in treating cutaneous leishmaniasis patients in an operational context was carried out in Chaparral, Colombia. After enrolment patients were followed-up for up to 100 days. Per protocol and intention-to-treat cure rates for 47 patients treated using thermotherapy (one-time 50 degrees C applications for 30s) were 100 and 19%, respectively. Per protocol and intention-to-treat cure rates for meglumine antimoniate (20 mg/kg body weight administered intramuscularly for 21 d) were 78 and 23%, respectively. (C) 2008 Royal Society of Tropical Medicine and Hygiene. Pubtished by Elsevier Ltd. All rights reserved.

引用

页码：703 / 706

页数：4

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