Dynamin and endocytosis

被引：109

作者：

Sever, S

机构：

[1] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA

[2] Dana Farber Canc Inst, Boston, MA 02115 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2002年 / 14卷 / 04期

关键词：

D O I：

10.1016/S0955-0674(02)00347-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The GTPase dynamin is essential for endocytosis, but its mechanism of action remains uncertain. Structures of its GTPase domain, as well as that of assembled dynamin, have led to major advances in understanding the structural basis of its mode of action. Novel data point more clearly than ever towards a role for this protein in the actin cytoskeleton, mitogen-activated protein kinase signaling and apoptosis, suggesting that dynamin might be a signaling GTPase.

引用

收藏

页码：463 / 467

页数：5

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