Synthesis of the new triheterocyclic system C3N-C4N-C6N.: 3-aryl-2,5,5-trimethyl-9a-methylsulfanyl-9-phenoxy-4,5,6,8,9,9a-hexahydro-3H-azeto[1,2-a]pyrrolo[3,2-c]azepin-8-ones

被引：5

作者：

Martínez, R

Avila-Zárraga, JG

López-López, G

Nava-Salgado, VO

机构：

[1] Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico

[2] Univ Nacl Autonoma Mexico, Fac Quim, Mexico City 04510, DF, Mexico

来源：

HETEROCYCLES | 2000年 / 53卷 / 03期

关键词：

D O I：

10.3987/COM-99-8662

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The regio- and stereoselective synthesis of the cis-3-aryl-2,5,5-trimethyl-9a-methylsulfanyl-9-phenoxy-4,5,6,8,9,9a-hexahydro-3H-azeto[1,2-a]pyrrolo[3,2-c]azepin-8-ones (1) was performed. A four-step sequence, which yields are good, constitutes the first synthetic way for the preparation of the first member of this new C3N-C4N-C6N series.

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页码：557 / +

页数：15

相关论文

共 36 条

[1] Origins of the stereodivergent outcome in the Staudinger reaction between acyl chlorides and imines [J].

Arrieta, A ;

Lecea, B ;

Cossío, FP .

JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (17) :5869-5876

[2]

Asseline U, 1997, NEW J CHEM, V21, P5

[3] ACYCLIC STEREOSELECTION - ERYTHROSELECTIVE ALDOL CONDENSATION OF 4-ACYL-2,3-DIHYDRO-4H-1,4-BENZOTHIAZINE AND 10-ACYLPHENOTHIAZINE [J].

BABUDRI, F ;

DINUNNO, L ;

FLORIO, S .

TETRAHEDRON LETTERS, 1983, 24 (36) :3883-3886

[4] ENEHYDRAZINES .22. LACTAMS FROM 1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES [J].

BARDAKOS, V ;

SUCROW, W .

CHEMISCHE BERICHTE-RECUEIL, 1978, 111 (05) :1780-1788

[5]

BRESLIN HJ, 1995, J MED CHEM, V38, P771, DOI 10.1021/jm00005a005

[6] ACYCLIC STEREOSELECTION .48. REVERSAL OF STEREOCHEMISTRY IN THE ALDOL REACTIONS OF A CHIRAL BORON ENOLATE [J].

DANDA, H ;

HANSEN, MM ;

HEATHCOCK, CH .

JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (01) :173-181

[7] ENANTIOSELECTIVE ALDOL CONDENSATIONS .2. ERYTHRO-SELECTIVE CHIRAL ALOL CONDENSATIONS VIA BORON ENOLATES [J].

EVANS, DA ;

BARTROLI, J ;

SHIH, TL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (08) :2127-2129

[8] INVITRO ASSESSMENT OF N-[2-(DIMETHYLAMINO)ETHYL]ACRIDINE-4-CARBOXAMIDE, A DNA-INTERCALATING ANTITUMOR DRUG WITH REDUCED SENSITIVITY TO MULTIDRUG RESISTANCE [J].

FINLAY, GJ ;

MARSHALL, E ;

MATTHEWS, JHL ;

PAULL, KD ;

BAGULEY, BC .

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1993, 31 (05) :401-406

[9] The novel cyclopropapyrroloindole (CPI) bisalkylators bearing 3,3′-(1,4-phenylene)diacryloyl group as a linker [J].

Fukuda, Y ;

Seto, S ;

Furuta, H ;

Ebisu, H ;

Oomori, Y .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (15) :2003-2004

[10]

GAJDA T, 1979, SYNTHESIS-STUTTGART, P549

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