ARF1 regulatory factors and COPI vesicle formation

被引：78

作者：

Spang, A ^{[1
]}

机构：

[1] Max Planck Gesell, Friedrich Miescher Lab, D-72076 Tubingen, Germany

来源：

CURRENT OPINION IN CELL BIOLOGY | 2002年 / 14卷 / 04期

关键词：

D O I：

10.1016/S0955-0674(02)00346-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Understanding the biosynthetic pathways involved in cellular transport is an important issue in cell biology. More than a hundred years after the discovery of the Golgi apparatus, we still do not understand the regulation of vesicular transport to, within and from the Golgi apparatus. Recently, however, it has become clear that cargo might not simply be a passive passenger, and that ADP-ribosylation factor (ARF) GAPs are not only GTPase-activating proteins for ARF, but might play crucial roles in regulating coat protein complex I vesicle formation.

引用

页码：423 / 427

页数：5

共 39 条

[31] Functional rafts in cell membranes [J].

Simons, K ;

Ikonen, E .

NATURE, 1997, 387 (6633) :569-572

[32] The ADP ribosylation factor-nucleotide exchange factors Gea1p and Gea2p have overlapping, but not redundant functions in retrograde transport from the Golgi to the endoplasmic reticulum [J].

Spang, A ;

Herrmann, JM ;

Hamamoto, S ;

Schekman, R .

MOLECULAR BIOLOGY OF THE CELL, 2001, 12 (04) :1035-1045

[33] Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes [J].

Spang, A ;

Matsuoka, K ;

Hamamoto, S ;

Schekman, R ;

Orci, L .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (19) :11199-11204

[34] Nucleation of COPII vesicular coat complex by endoplasmic reticulum to Golgi vesicle SNAREs [J].

Springer, S ;

Schekman, R .

SCIENCE, 1998, 281 (5377) :698-700

[35] A primer on vesicle budding [J].

Springer, S ;

Spang, A ;

Schekman, R .

CELL, 1999, 97 (02) :145-148

[36] Glycosphingolipids are required for sorting melanosomal proteins in the Golgi complex [J].

Sprong, H ;

Degroote, S ;

Claessens, T ;

van Drunen, J ;

Oorschot, V ;

Westerink, BHC ;

Hirabayashi, Y ;

Klumperman, J ;

van der Sluijs, P ;

van Meer, G .

JOURNAL OF CELL BIOLOGY, 2001, 155 (03) :369-379

[37] RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport [J].

Sullivan, BM ;

Harrison-Lavoie, KJ ;

Marshansky, V ;

Lin, HY ;

Kehrl, JH ;

Ausiello, DA ;

Brown, D ;

Druey, KM .

MOLECULAR BIOLOGY OF THE CELL, 2000, 11 (09) :3155-3168

[38] Arfaptin 1, an ARF-binding protein, inhibits phospholipase D and endoplasmic reticulum Golgi protein transport [J].

Williger, BT ;

Ostermann, J ;

Exton, JH .

FEBS LETTERS, 1999, 443 (02) :197-200

[39] Localization of large ADP-ribosylation factor-guanine nucleotide exchange factors to different golgi compartments:: Evidence for distinct functions in protein traffic [J].

Zhao, XH ;

Lasell, TKR ;

Melançon, P .

MOLECULAR BIOLOGY OF THE CELL, 2002, 13 (01) :119-133

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