DNA strand breaks induced by 0-4 eV electrons: The role of shape resonances

被引：438

作者：

Martin, F ^{[1
]}

Burrow, PD

Cai, ZL

Cloutier, P

Hunting, D

Sanche, L

机构：

[1] Univ Sherbrooke, Fac Med, Sherbrooke, PQ J1H 5N4, Canada

[2] Univ Nebraska, Dept Phys & Astron, Lincoln, NE 68588 USA

来源：

PHYSICAL REVIEW LETTERS | 2004年 / 93卷 / 06期

基金：

加拿大健康研究院;

关键词：

D O I：

10.1103/PhysRevLett.93.068101

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Collisions of 0-4 eV electrons with thin DNA films are shown to produce single strand breaks. The yield is sharply structured as a function of electron energy and indicates the involvement of pi(*) shape resonances in the bond breaking process. The cross sections are comparable in magnitude to those observed in other compounds in the gas phase in which pi(*) electrons are transferred through the molecule to break a remote bond. The results therefore support aspects of a theoretical study by Barrios et al. [J. Phys. B 106, 7991 (2002)] indicating that such a mechanism could produce strand breaks in DNA.

引用

页码：068101 / 1

页数：4

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