DNA strand breaks induced by 0-4 eV electrons: The role of shape resonances

被引：438

作者：

Martin, F ^{[1
]}

Burrow, PD

Cai, ZL

Cloutier, P

Hunting, D

Sanche, L

机构：

[1] Univ Sherbrooke, Fac Med, Sherbrooke, PQ J1H 5N4, Canada

[2] Univ Nebraska, Dept Phys & Astron, Lincoln, NE 68588 USA

来源：

PHYSICAL REVIEW LETTERS | 2004年 / 93卷 / 06期

基金：

加拿大健康研究院;

关键词：

D O I：

10.1103/PhysRevLett.93.068101

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Collisions of 0-4 eV electrons with thin DNA films are shown to produce single strand breaks. The yield is sharply structured as a function of electron energy and indicates the involvement of pi(*) shape resonances in the bond breaking process. The cross sections are comparable in magnitude to those observed in other compounds in the gas phase in which pi(*) electrons are transferred through the molecule to break a remote bond. The results therefore support aspects of a theoretical study by Barrios et al. [J. Phys. B 106, 7991 (2002)] indicating that such a mechanism could produce strand breaks in DNA.

引用

页码：068101 / 1

页数：4

共 24 条

[11] Electron attachment to uracil:: Effective destruction at subexcitation energies -: art. no. 188104 [J].

Hanel, G ;

Gstir, B ;

Denifl, S ;

Scheier, P ;

Probst, M ;

Farizon, B ;

Farizon, M ;

Illenberger, E ;

Märk, TD .

PHYSICAL REVIEW LETTERS, 2003, 90 (18) :4

[12]

Hotop H, 2003, ADV ATOM MOL OPT PHY, V49, P85

[13] Single, double, and multiple double strand breaks induced in DNA by 3-100 eV electrons [J].

Huels, MA ;

Boudaïffa, B ;

Cloutier, P ;

Hunting, D ;

Sanche, L .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (15) :4467-4477

[14]

JORGENSEN WL, 1973, ORGANIC CHEM BOOK OR

[15] ELECTRON-ENERGY-LOSS DISTRIBUTIONS IN SOLID, DRY DNA [J].

LAVERNE, JA ;

PIMBLOTT, SM .

RADIATION RESEARCH, 1995, 141 (02) :208-215

[16] Density functional theory studies of electron interaction with DNA: Can zero eV electrons induce strand breaks? [J].

Li, XF ;

Sevilla, MD ;

Sanche, L .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (45) :13668-13669

[17]

MODELLI A, IN PRESS

[18] Dissociative electron attachment to DNA [J].

Pan, X ;

Cloutier, P ;

Hunting, D ;

Sanche, L .

PHYSICAL REVIEW LETTERS, 2003, 90 (20) :4

[19] DISSOCIATIVE ATTACHMENT AS A PROBE OF THE DISTANCE DEPENDENCE OF INTRAMOLECULAR ELECTRON-TRANSFER [J].

PEARL, DM ;

BURROW, PD ;

NASH, JJ ;

MORRISON, H ;

NACHTIGALLOVA, D ;

JORDAN, KD .

JOURNAL OF PHYSICAL CHEMISTRY, 1995, 99 (33) :12379-12381

[20] DISSOCIATIVE ATTACHMENT AS A PROBE OF INTRAMOLECULAR ELECTRON-TRANSFER [J].

PEARL, DM ;

BURROW, PD ;

NASH, JJ ;

MORRISON, H ;

JORDAN, KD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (21) :9876-9877

← 1 2 3 →