Dendritic polymer macromolecular carriers for drug delivery

被引：494

作者：

Patri, AK ^{[1
]}

Majoros, IJ ^{[1
]}

Baker, JR ^{[1
]}

机构：

[1] Univ Michigan, Dept Internal Med, Ctr Biol Nanotechnol, Ann Arbor, MI 48109 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2002年 / 6卷 / 04期

关键词：

D O I：

10.1016/S1367-5931(02)00347-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Dendrimers are synthetic, highly branched, mono-disperse macromolecules of nanomater dimensions. Started in the mid-1980s, the research investigations into the synthetic methodology, physical and chemical properties of these macromolecules are increasing exponentially with growing interest in this field. Potential applications for dendrimers are now forthcoming. Properties associated with these dendrimers such as uniform size, water solubility, modifiable surface functionality and available internal cavities make them attractive for biological and drug-delivery applications.

引用

页码：466 / 471

页数：6

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