Proteomic biomarkers for autoimmune disease

被引：38

作者：

Hueber, Wolfgang

Robinson, William H.

机构：

[1] Palo Alto VA Hlth Care Syst, GRECC, Palo Alto, CA 94304 USA

[2] Stanford Univ, Sch Med, Div Immunol & Rheumatol, Dept Med, Stanford, CA 94305 USA

来源：

PROTEOMICS | 2006年 / 6卷 / 14期

关键词：

autoantibody profiling; autoimmune disease; biomarker; phosphoproteome; spectrometry;

D O I：

10.1002/pmic.200600017

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Autoimmune diseases affect 3% of the world population, yet the diagnosis and classification of autoimmune diseases remain based on clinical examination combined with traditional laboratory tests and imaging studies. The development of genomic and proteomic technologies provides an unprecedented ability to identify novel biosignatures to diagnose, classify, and guide therapeutic decision making in patients with autoimmune disease. In this article, we review recent advances in proteomics technologies and their application to autoimmune disease.

引用

页码：4100 / 4105

页数：6

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