Dengue in Southeast Asia: epidemiological characteristics and strategic challenges in disease prevention

被引:161
作者
Ooi, Eng-Eong [1 ,2 ]
Gubler, Duane J. [2 ,3 ]
机构
[1] DSO Natl Labs, Singapore 117510, Singapore
[2] Duke NUS Grad Med Sch Singapore, Singapore, Singapore
[3] Univ Hawaii, Asia Pacific Inst Trop Med & Infect Dis, Honolulu, HI 96822 USA
来源
CADERNOS DE SAUDE PUBLICA | 2009年 / 25卷
关键词
Dengue; Disease Prevention; Communicable Diseases; AEDES-ALBOPICTUS SKUSE; HEMORRHAGIC-FEVER; SINGAPORE-CITY; AEGYPTI L; PUERTO-RICO; SEVERITY; CLASSIFICATION; SURVEILLANCE; TRANSMISSION; PATHOGENESIS;
D O I
10.1590/S0102-311X2009001300011
中图分类号
R1 [预防医学、卫生学];
学科分类号
100235 [预防医学];
摘要
Dengue emerged as a public health burden in Southeast Asia during and following the Second World War and has become increasingly important, with progressively longer and more frequent cyclical epidemics of dengue fever/dengue hemorrhagic fever. Despite this trend, surveillance for this vector-borne viral disease remains largely passive in most Southeast Asian countries, without adequate laboratory support. We review here the factors that may have contributed to the changing epidemiology of dengue in Southeast Asia as well as challenges of disease prevention. We also discuss a regional approach to active dengue virus surveillance, focusing on urban areas where the viruses are maintained, which may be a solution to limited financial resources since most of the countries in the region have developing economies. A regional approach would also result in a greater likelihood of success in disease prevention since the large volume of human travel is a major factor contributing to the geographical spread of dengue viruses.
引用
收藏
页码:S115 / S124
页数:10
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