A new synthetic route to 2-alkyl-4-aryl-1(2H)-isoquinolones and 2-alkyl-4-aryl-1,2,3,4-tetrahydroisoquinolines

被引：28

作者：

Couture, A

Deniau, E

Grandclaudon, P

Woisel, P

机构：

[1] Lab. de Chimie Organique Physique, URA CNRS 351, Univ. Sci. et Tecnologies de Lille I

来源：

TETRAHEDRON | 1996年 / 52卷 / 12期

关键词：

D O I：

10.1016/0040-4020(96)00092-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-Aryl and heteroaryl-1(2H)-isoquinolones have been prepared by base promoted cyclization of phosphorylated o-aroyl and heteroaroyl benzamides. Subsequent reduction of the carbonyl and styryl functions of the annulated products has given rise to 4-aryl-1,2,3,4-tetrahydroisoquinolines.

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页码：4433 / 4448

页数：16

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