Cortical network dynamics with time delays reveals functional connectivity in the resting brain

被引：94

作者：

Ghosh, A. ^{[1
]}

Rho, Y. ^{[2
]}

McIntosh, A. R. ^{[3
]}

Kotter, R. ^{[4
]}

Jirsa, V. K. ^{[1
,2
]}

机构：

[1] CNRS, Theoret Neurosci Grp, UMR6152, Inst Sci Mouvement, F-13288 Marseille 9, France

[2] Florida Atlantic Univ, Ctr Complex Syst & Brain Sci, Dept Phys, Boca Raton, FL 33431 USA

[3] Rotman Res Inst, Toronto, ON M6A 2E1, Canada

[4] Radboud Univ Nijmegen, Donders Ctr Neurosci, Dept Cognit Neurosci, NL-6525 EZ Nijmegen, Netherlands

来源：

COGNITIVE NEURODYNAMICS | 2008年 / 2卷 / 02期

关键词：

Resting brain; Default mode;

D O I：

10.1007/s11571-008-9044-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In absence of all goal-directed behavior, a characteristic network of cortical regions involving prefrontal and cingulate cortices consistently shows temporally coherent fluctuations. The origin of these fluctuations is unknown, but has been hypothesized to be of stochastic nature. In the present paper we test the hypothesis that time delays in the network dynamics play a crucial role in the generation of these fluctuations. By tuning the propagation velocity in a network based on primate connectivity, we scale the time delays and demonstrate the emergence of the resting state networks for biophysically realistic parameters.

引用

页码：115 / 120

页数：6

共 19 条

[1] Synchrony and clustering in heterogeneous networks with global coupling and parameter dispersion [J].

Assisi, CG ;

Jirsa, VK ;

Kelso, JAS .

PHYSICAL REVIEW LETTERS, 2005, 94 (01)

[2] The proactive brain: using analogies and associations to generate predictions [J].

Bar, Moshe .

TRENDS IN COGNITIVE SCIENCES, 2007, 11 (07) :280-289

[3] FUNCTIONAL CONNECTIVITY IN THE MOTOR CORTEX OF RESTING HUMAN BRAIN USING ECHO-PLANAR MRI [J].

BISWAL, B ;

YETKIN, FZ ;

HAUGHTON, VM ;

HYDE, JS .

MAGNETIC RESONANCE IN MEDICINE, 1995, 34 (04) :537-541

[4]

Breakspear M., 2007, Handbook of Brain Connectivity

[5]

DAUBECHIES I, 1992, LECT WAVELETS

[6] IMPULSES AND PHYSIOLOGICAL STATES IN THEORETICAL MODELS OF NERVE MEMBRANE [J].

FITZHUGH, R .

BIOPHYSICAL JOURNAL, 1961, 1 (06) :445-&

[7] The human brain is intrinsically organized into dynamic, anticorrelated functional networks [J].

Fox, MD ;

Snyder, AZ ;

Vincent, JL ;

Corbetta, M ;

Van Essen, DC ;

Raichle, ME .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (27) :9673-9678

[8] Functional connectivity in the resting brain: A network analysis of the default mode hypothesis [J].

Greicius, MD ;

Krasnow, B ;

Reiss, AL ;

Menon, V .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (01) :253-258

[9] Searching for a baseline: Functional imaging and the resting human brain [J].

Gusnard, DA ;

Raichle, ME .

NATURE REVIEWS NEUROSCIENCE, 2001, 2 (10) :685-694

[10] Network structure of cerebral cortex shapes functional connectivity on multiple time scales [J].

Honey, Christopher J. ;

Koetter, Rolf ;

Breakspear, Michael ;

Sporns, Olaf .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (24) :10240-10245

← 1 2 →