Cyclooxygenase inhibitory constituents from Houttuynia cordata

被引：39

作者：

Bauer, R

Probstle, A

Lotter, H

WagnerRedecker, W

Matthiesen, U

机构：

[1] UNIV MUNICH,INST PHARMAZEUT BIOL,D-80333 MUNICH,GERMANY

[2] FINNIGAN MAT GMBH,D-28197 BREMEN,GERMANY

[3] UNIV DUSSELDORF,SPURENELEMENTLABOR MED EINRICHTUNG,D-40225 DUSSELDORF,GERMANY

来源：

PHYTOMEDICINE | 1996年 / 2卷 / 04期

关键词：

Houttuynia cordata; Saururaceae; fatty acids; phytol; stigmast-4-ene-3,6-dione; pyridine alkaloids; LC-MS; cyclooxygenase inhibition;

D O I：

10.1016/S0944-7113(96)80073-0

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

The n-hexane extract of Houttuynia cordata was shown to inhibit prostaglandin synthase in vitro. Phytochemical examination led to the identification of five fatty acids (linolenic, linoleic, oleic, palmitic and stearic), cepharanone B, phytol and stigmast-4-ene-3,6-dione. The inhibitory ef feet of the extract on prostaglandin formation in vitro could be attributed mainly to linoleic and linolenic acid.

引用

页码：305 / 308

页数：4

共 20 条

[1]

PLACEBO-CONTROLLED TRIAL OF ESSENTIAL FATTY-ACID SUPPLEMENTATION IN ATOPIC-DERMATITIS [J].