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Bioactive ceramics: the effect of surface reactivity on bone formation and bone cell function

被引：841
作者：
Ducheyne, P [1 ]
Qiu, Q [1 ]
机构：
[1] Univ Penn, Dept Bioengn, Ctr Bioact Mat & Tissue Engn, Philadelphia, PA 19104 USA
来源：
BIOMATERIALS | 1999年 / 20卷 / 23-24期
关键词：
bioactivity; bioactive materials; tissue engineering;
D O I：
10.1016/S0142-9612(99)00181-7
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Surface reactivity is one of the common characteristics of bone bioactive ceramics. It contributes to their bone bonding ability and their enhancing effect on bone tissue formation. During implantation, reactions occur at the material-tissue interface that lead to time-dependent changes in the surface characteristics of the implant material and the tissues at the interface. This review describes some of the current concepts regarding the surface reactivity of bone bioactive materials and its effect on attachment, proliferation, differentiation and mineralization of bone cells. (C) 1999 Elsevier Science Ltd. All rights reserved.
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页码：2287 / 2303
页数：17
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